Abstract
Conclusions
The scarcity of cell divisions among the interstitial cells of the testes of PU-treated animals makes unlikely the conclusion that the increase in the number of these cells is due, except to a slight degree, to their mitosis. Observations were presented which support the opinions of Esaki, 1 and others that the interstitial cells have an extrinsic origin. Other data, to be presented elsewhere, indicate that certain intertubular connective tissue elements are differentiated into active secreting Leydig cells by the action of the gonadotropic hormones of pregnancy urine.
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