Abstract
Summary
Beta-methylcholine-urethane, a drug which has been reported to have beneficial effects in cases of postoperative abdominal distention, causes a marked increase in the tonus and the amplitude of rhythmic contractions of innervated or of denervated jejunal segments of unmedicated dogs. The drug opposes inhibition of the intestine by reflexly activated sympathetic nerves or inhibition by the sympathin released as a result of the activity of these nerves. The effects of the drug on intestinal motility are prevented by atropinization.
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