Abstract
Summary and Conclusions
From the data presented it is evident that there was considerable variation in the total amount of bile obtained in each animal. The mean flow of bile per hour per kilo of body weight was 3.4 cc in the first 2 hours in 47 rabbits, 2.64 cc in the second 2 hours in 33 of the 47 rabbits, and 2.33 cc during the third 2 hours of the experiments in 19 of the 47 rabbits. Thus there was a gradual decrease in the flow of bile as the experiments proceeded. This decrease was more marked in those experiments in which the bile was collected against a hydrostatic pressure greater than that of the atmosphere. During the entire period of each experiment the gallbladder was resorbing half the volume of its content per hour, i. e., about 0.5 cc per hour per kilo of body weight, 3 , 4 hence the amount of bile actually produced per hour by each rabbit was greater than that recorded.
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