Abstract
The concentration of androgenic activity found in the urine of human males has been shown to be high in comparison to that found in the urine of stallions, bulls and rams. 1 It becomes of interest, therefore, to study the quantitative excretion of androgenic substances in the urine of the adult male monkey.
Three normal adult rhesus monkeys of known fertility weighing between 6.9 and 10.0 kg were chosen for the urine collections. Four samples from each monkey were collected over periods of 72 or 96 hours. The method employed for the quantitative extraction of androgenic and estrogenic substances from the urines has been previously described. 2 The androgenic activity was assayed by means of the day-old chick's comb, 3 while the estrogenic activity was determined by means of the estrus reaction in the adult spayed female mouse.
The results of the assays of both estrogenic and androgenic activity are listed in Table I. It is shown that the adult male monkey excretes both estrogenic and androgenic substances. The estrogenic activity varied from 11.1 to 2.5 I.U. per 24 hours, while the anidrogenic activity varied from 1.0 to 4.7 I.U. per 24 hours.
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