Abstract
Conclusions
Studies of the conditions which permit or prevent the viruses of vesicular stomatitis and equine encephalomyelitis to invade the CNS of mice and guinea pigs have thus far disclosed that depending upon the age or species of the host there may be changes or variations in localized sites, e.g., in terminal, specialized nerve endings, in special areas of the CNS, blood vessels, etc., which can prevent the virus from invading or progressing in the CNS—changes in different tissues functioning as barriers for different viruses depending upon the mode of CNS invasion utilized by the virus.
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