Abstract
Conclusion
A study is presented in which the administration of testosterone propionate interrupted regular menstrual cycles in a young woman. Menstruation was resumed after cessation of treatment with this hormone. Vaginal smears showed that during the period of induced amenorrhea there was a replacement of the normal smear picture by one of the typical atrophic menopausal type, indicating a temporary suppression of ovarian follicular activity. This smear type was preceded and followed by characteristic intermediate stages and persisted throughout the course of treatment, and for a short time afterward. It was then followed by gradual resumption of follicular activity and a normal smear picture. The next menses occurred 28 days after the last dose of Oreton and about 12 to 13 days after the establishment of follicular activity.
This study furnishes a method for controlling the use of male sex hormone in women, and for inducing a temporary cessation of their menstrual cycle.
Get full access to this article
View all access options for this article.