Abstract
Summary and Conditions
The various fractions of chick brain, namely, the alcohol extract fraction, the trichloracetic acid extract fraction, and the fraction remaining after both extractions, were analyzed for their phosphorus content. In comparing the values obtained from chicks on a normal ration with those obtained from chicks receiving rations low in one of the essential factors (vitamin A, vitamin B4, and encephalomalacia) the following results were obtained.
The ester phosphorus of the trichloracetic acid fraction was markedly reduced in the deficiency diseases, while the inorganic phosphorus was increased but not to the same extent as the former was reduced. The alcohol extract phosphorus fraction was only slightly increased. The phosphorus of the brain residue after alcohol and trichloracetic acid extractions as well as the total phosphorus content of brain was unaffected. Further, the amount of alcohol-soluble material of the brains was similar in both deficient and control chicks. Certain nutritional deficiencies, among them the lack of the encephalomalacia factor, vitamin A, or B4, cause a disturbance of normal phosphorus metabolism in the brain of the chick.
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