Abstract
Summary
The cells of the autonomic ganglia of cats deprived of their adrenal glands for a sufficient time to bring about classica1 signs of adrenal insufficiency present definite degenerative changes. These changes vary in degree directly with the severity of the insufficiency as indicated by the physical signs. No definite statement can be made as to the significance of these findings in so far as our studies are concerned but the suggestion is offered that autonomic ganglion cell degeneration may explain some of the vasomotor disturbances in adrenal insufficiency. Neither is it possible to offer an explanation as to how the adrenal insufficiency affects the ganglion cells–whether as a part of a general metabolic disturbance or in some more direct. or even more complex, manner.
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