Effect of Massive Doses of Adrenal Cortical Hormone on the Albino Rat. ∗

Abstract

Conclusion

The negative results obtained from the feeding of niassive doses of charcoal adsorblate, prepared from bleef adrenal cortex may indicate that the sulrstance in the adrenal cortex, which stiniulates the reproductive system, is a different hormone from that demonstrated by Harrop 1 as affecting the metabolism of salt and water and it may not be extracted by the methods at present in use for extracting the latter. The excellent condition of the experimental animals is evidence that the substance is not toxic.