Abstract
Conclusions
1. Hemolytic streptococci of human origin, when tested for fibrinolytic activity in 2% and 0.05% glucose-broths, may be classified in one of the following groups: (a) production in 2% only; (b) in 0.05% only; (c) in both 2% and 0.05%; and (d) no production in either.
Properties of the 2% glucose-broth fibrinolysin (a): This type of fibrinolysin inhibits clotting; it is effective toward human and animal plasma, but only when used undiluted; it is thermostable; and was not neutralized by specific streptococcal antisera.
The fibrinolysin of groups (b) and (c), even in high dilutions, lyses human plasma but not animal plasma; it is thermostable, and may be neutralized by streptococcal antisera.
Serum-broth fibrinolysin resembles 0.05% glucose-broth fibrinolysin, but is heat-labile.
2. S. viridans, enterococcus, and pneumococcus, when cultivated in 2% glucose-broth, may produce a fibrinolysin which has the same properties as the fibrinolysin produced by hemolytic streptococci in 2% glucose-broth.
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