Abstract
Summary
In 4 cases of Graves disease with an average basal metabolic rate of +33%, the arterio-venous oxygen difference was found to be decreased by 37%. The average cardiac output was 8.1 liters per minute compared to a normal of 4.2, representing an increase of 93%. The relation of the present findings to those previously reported, to the question of method of cardiac output determination, and to the possible nature of the underlying metabolic disturbance in Graves disease is briefly discussed.
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