Abstract
Summary
1. The nasal mucosa of the intact monkey (Macaca mulatta) responds to the administration of oestrogenic substances, crystalline oestrone and oestriol, and emmenin in the manner of and synchronously with the changes known to occur in the nipple, sex-skin, face and back. 2. The response is most clearly Seen in the “middle” and inferior conchae which show reddening and/or swelling. 3. The oestrogenic substances mentioned are effective in both females and males, immature and adult animals. 4. The effect can be produced in female castrates by crystalline oestrone and oestriol. 5. In the untreated immature and adult female animal peaks of nasal activity normally occur, chiefly “pre-menstrual” in time, and at intervals of about 28 days. 6. Such naturally occurring nasal cyclical activity is most marked in the autumn months, which is the mating season.
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