Abstract
The writers 1 , 2 have previously shown that a diet deficient in vitamin G has a pronounced limiting effect on the numbers of oocysts discharged by rats infected with the coccidium Eimeria miyairii. The present work was undertaken to ascertain the effect of vitamin G from sources other than yeast.
Experiment I. Thirteen rats were kept for 14 days on a balanced growing ration (Steenbock's) containing corn meal, linseed oil meal, casein, alfalfa, skim milk and salt. Subsequent to infection with 1500 oocysts of E. miyairii daily for 5 days this lot eliminated oocysts as follows, in terms of ten millions: 23, 28, 20, 19, 23, 13, 16, 27, 30, 17, 29, 14, 36; mean, 22.69. Thirteen rats were given the basal ration 2 made up to 10% with powdered yeast. These eliminated ten millions of oocysts as follows: 14, 24, 32, 18, 14, 12, 22, 34, 31, 23, 32, 17, 18; mean, 22.385. The coccidium-growth promoting factor in yeast is hereby shown to be present likewise in other materials, for the analysis of variance test 3 showed the data of the 2 series not to be significantly different.
Experiment II. The following low-G ration was prepared: white corn meal, 25; beet sugar, 48; wheat gluten, 10; casein, acid-water extracted, 8; salt mixture, 2; butter, 5; cod liver oil, 2. The reference diet was the growing ration. In the first trial 7 rats on the low-G diet for 2 weeks discharged oocysts as follows, in millions, after infection: 48, 91, 165, 95, 94, 34, 117; mean, 92. The same for reference series: 301, 144, 273, 153, 180, 231, 419; mean, 243. In the second trial: low-G series,—62, 82, 32, 63, 59, 37, 61, 65; mean, 57.62; reference series,—194, 128, 121, 35, 204, 88, 206; mean, 139.43.
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