Abstract
The transmission of Hodgkin's disease to animals has so far failed and auto-transplantation in man has also failed. Direct injection of Hodgkin's tissue into the lymphatics has not been tried. This method, applied to dogs, seemed of promise as Hodgkin's disease has been described in dogs. 1
Using the method of Drinker the paw lymphatic of 3 large shepherd dogs was cannulated and fresh saline emulsions of diseased lymph nodes were injected. In 2 dogs the injections were repeated so that in all the material from 5 patients with Hodgkin's disease was used. After this the dogs were observed clinically from 7 months to 3 years and then killed. On necropsy of each dog no evidence of disease resembling Hodgkin's could be found.
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