Oral Toxicity of Ortho-n-alkylphenols to White Rats. ∗

Abstract

Conclusions

1. The oral toxicity of ortho-n-alkylphenols to white rats decreases with the increase in length of the alkyl radical. 2. This decrease in toxicity with increase in length of the alkyl radical corresponds to our toxicity findings in series of 6-alkyl-meta-cresols and 4-n-alkylresorcinols. 3. Ortho-n-alkylphenols are less toxic than n-alkylresorcinols with the corresponding length of alkyl chains but show little difference in toxicity from the 6-alkyl-meta-cresols with the same number of substituted carbon atoms.