Abstract
Summary
1. Both the gonadotropic hormone of pregnancy urine and that prepared from pituitary tissue lead to a more marked ovarian response in the pregnant than in the non-pregnant rat. This increased responsiveness to gonadotropic hormones continues for some time post-partum if nursing is not allowed. 2. In hypophysec-tomized rats urinary preparations lead only to thecal luteinization, even when given during gestation. 3. Similarly in lactating and pregnant rats, the urinary preparation leads to thecal luteinization, but granulosa luteinization also occurs at the same time. Pituitary preparations do not lead to thecal luteinization during lactation. 4. Neither the urinary nor the pituitary preparation is able to produce the usual uterine reaction when given during lactation.
Get full access to this article
View all access options for this article.