Absorption of Strychnine Sulphate from Strangulated Segments of Bowel. ∗

Abstract

Conclusions

1. Strychnine sulphate is quickly absorbed from the lumen of the normal bowel and from the peritoneal cavity. 2. Interference with the blood supply of a segment of bowel prevents or greatly delays the absorption of strychnine from the lumen. 3. complete arrest of blood flow to (arterial occlusion) or from the bowel (venous occlusion) probably precludes absorption through the misrepresenter vessels. 4. Evidence of transperitoneal absorption was demonstrated in some of these experiments but only through gut wall whose nutrition was seriously damaged. In the absence of gross perforation or rupture of the gut wall, transperitoneal absorption is slight even in the presence of a badly damaged wall.