Abstract
Conclusions
The colloidal dyes congo red, vital red, rose bengal, and mercurochrome, tried under a variety of conditions, failed to protect the majority of guinea pigs and pigeons against the typical symptoms of anaphylactic shock. These negative results do not support the positive claims of Nikolaiev and Goldberg, who used congo red and trypan blue. It is suggested that the results with these colloidal dyes point to fundamental differences in the tissue reactivities of proteins and of drugs and toxins.
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