Abstract
It is known that a lipemia may occur in diabetes. Depancreatized dogs develop a lipemia which is more marked and appears earlier than that of phlorhizinized dogs. 1 However, the character of the fatty acids mobilized has not been determined. Hence in the present study the iodine numbers have been ascertained on 12 depancreatized and 7 phlorhizinized dogs. Iodine number and total fat content of each sample of blood were estimated, the former according to the modification of Gibson and Howard 2 and the latter according to that of Himwich, Friedman and Spiers. 3 An increase in the blood fat was always accompanied by a decrease in the iodine number. Typical experiments are presented in Table I.
Since the iodine number depends on the fraction iodine absorbed/total fatty acids the diminution of the iodine number indicates that the amount of unsaturated fatty acids does not vary as much as the saturated, i. e. saturated rather than unsaturated fatty acids are mobilized.
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