Abstract
The presence of severe liver damage following cholecystgastrostomy and cholecystduodenostomy in the dog has been demonstrated by Lehman, 1 Horsley, 2 Beaver, 3 and Gatewood and Stanley. 4 The changes noted have been of varying degrees, from simple lymphangitis to extensive necrosis and abscess formation. All agree that in their experiments a hepatitis of varying degrees developed following anastomosis of the gallbladder to the gastro-intestinal tract. However, these authors failed to obtain specimens of the liver for histological study with concomitant bacteriological studies of the normal liver, stomach, or duodenum in order that a comparison could be made with sections of liver removed at varying intervals after the anastomosis of the gallbladder to the stomach and duodenum.
In 1909 Walbach and Saiki 5 demonstrated that areas of necrosis occurred in the liver of normal dogs.
Previously I reported on the bacteriology of the liver before cholecystgastrostomy and cholecystduodenostomy followed by a second bacteriological check-up 15 days after the first operation. I found practically no changes in the bacterial flora of the liver after cholecystgastrostomy and cholecystduodenostomy.
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