Abstract
The metabolism of blood cells can be estimated from their glycolytic activity in vitro. This rate of glycolysis has been studied in the blood of patients with pernicious anemia during a remission induced by liver extract. In all of 5 cases the amount of sugar glycolyzed increased abruptly at the beginning of the remission. In 2 of the 5 cases the increased glycolysis during the reticulocyte crisis could he explained by an increase in erythrocytes and leucocytes. In the other 3 cases some of the increased glycolysis seemed to be attributable to the increase in the reticulocytes per se. This might indicate that young blood cells have a more active metabolism than adult cells.
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