Ephedrine Hydrochloride on the Excised Ureter of the Dog

Abstract

Conclusion

1. Ephedrine hydrochloride is mainly stimulant to the excised ureter of the dog. 2. The qualitative effect of ephedrine hydrochloride on the dog's ureter closely resembles that produced by epinephrine. 3. Ephedrine hydrochloride and epinephrine differ widely quantitatively when measured by the reaction of the surviving ureter to these agents, the latter being in some experiments about 200 times as stimulant as ephedrine. 4. The depression of the dog's ureter which appears after the use of the more concentrated solutions of ephedrine hydrochloride, invariably follows a rather extended period of stimulation, a period in which tonus, rate and amplitude of contracticm, either singly or collectively, may be increased.