Abstract
The mammary tree of adult virginal rats invariably undergoes some hyperplasia after a month of daily treatment with alkaline extracts of the anterior hypophysis, solutions very rich in growth hormone and almost completely devoid of the hormone which stimulates the ovaries of immature rodents to precocious development. By more chronic treatment with such an extract this can be brought to true milk secretion. Mammary hyperplasia takes place with more speed after treatment with the anterior hypophyseal ovary-stimulating hormone (bovine or rat hypophysis implant, or extracts of placenta and of the urine of pregnant women). The hyperplasia is, in fact, remarkable after only 10 days dosage with the latter methods.
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