Abstract
Conclusions
1. The administration of the ash of liver to 2 patients with typical pernicious anemia resulted in the appearance of some of the preliminary phenomena of a remission, in particular an increase in the percentage of reticulocytes. In neither case did a true remission occur until Minot's liver extract 343 was given.
2. The substance responsible for the above was apparently lost or inactivated by dissolving the ash in hydrochloric acid, neutralizing with NaOH, and evaporating the salts to dryness.
Get full access to this article
View all access options for this article.