Abstract
Parathyroid glands from oxen were extracted with acidified alcohol. Lipins and proteins were removed from the extract. Crystalline material was obtained by concentration which increases definitely the calcium content of the blood when dissolved in Ringer solution and injected into the circulation. Its effects upon the calcium content of the blood have been compared with those of adrenalin, pituitrin and insulin. Whether this crystalline material is the active calcium-mobilizing substance in the gland or merely a carrier of it in the preparation, remains to be determined. Its separation is additional evidence in favor of the view that the parathyroid glands secrete a hormone that influences the calcium content of the blood.
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