The glycogen content of the tissues of diabetic animals and the influence of adrenalin thereon

Abstract

Conclusions

I. Diabetic dogs contain glycogen in their muscles to the extent of 0.150 per cent. even after seven days of fasting and diabetes; residual glycogen.

II. This glycogen can be completely driven out by means of adrenalin.

III. Deglycogenized diabetic animals even during a period of prolonged fasting and diabetes are capable of reforming their lost residual glycogen.

IV. Failure on the part of an animal to show extra glucose elimination during the period of deglycogenization does not mean that the substance is not glucogenetic.

V. The conclusions of Sansum and Woodyatt that acetaldehyde is not glucogenetic nor antiketogenetic are objected to as in valid.