Abstract
The effects of progressive hemorrhage were studied on the dog under morphine-urethane anesthesia. We found that the greater the hemorrhage the greater the reduction in the amount of oxygen consumed and that a hemorrhage amounting to 1/2 per cent, of the body weight may elicit a decided reduction. Subsequent injection of gum-saline, bringing the blood volume back to normal, increased the amount of oxygen consumed. The amount of oxygen consumed immediately after an injection was greater than the consumption a few minutes later. We believe this, along with the decreased amount of oxygen consumed, points to an oxygen hunger during a period of decreased blood-volume. The results here reported are in agreement with those recently published by Doi. 1
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