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Examination of Rat Placental Lactogen and Prolactin at 6-hr Intervals during Midpregnancy

Experimental Biology and Medicine

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Research article

First published online September, 1983

Examination of Rat Placental Lactogen and Prolactin at 6-hr Intervals during Midpregnancy

and

Volume 173, Issue 4

https://doi.org/10.3181/00379727-173-41691

Abstract

The Nb₂ node lymphoma cell bioassay was verified in our laboratory as a sensitive, reproducible, and accurate bioassay for measurement of serum rat placental lactogen (rPL). Blood samples taken every 6 hr during pregnancy showed a significant peak of rPL secretion in the late afternoon on Day 11. The inverse relationship between rPL and nocturnal prolactin (PRL) surges is shown.

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