Abstract
Abstract
We have classified 28 hybridomas to the RS virus glycoproteins, VP66, VP84, by virus neutralization, RIP, and RIA tests. Without resorting to RIP, a combination of neutralization tests and RIA on BCH4 and RS/HO cells could be used to classify 79% of the hybridomas antibodies correctly. VP66 contains major determinants for virus neutralization since 11/13 hybridoma antibodies to this protein neutralized RS virus while 0/15 hybridoma antibodies to VP84 neutralized the virus.
Get full access to this article
View all access options for this article.