Abstract
Abstract
The mode of neonatal herpes simplex virus types 1 and 2 infection in guinea pigs was explored. There was no evidence of transplacental transmission of either virus type from mother to fetus following genital infection of the former. Infectious virus was not recoverable from placenta, cord blood, or amniotic fluid following either genital or intracardiac inoculation of HSV-2 into pregnant guinea pigs. However, a low rate of neonatal transmission of HSV-2 from mother to newborn via an infected birth canal during delivery was demonstrated.
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