Abstract
Abstract
Distribution of poly- and monoglutamate forms of folate coenzymes was studied in the whole egg, the nonembryonic portion of the egg, and in the embryo at various stages of development. Total folate activity of the nonembryonic portion decreases significantly after 12 days of incubation, while the folate activity of the embryo gradually increases. In the nonembryonic portion of the egg folates are present in monoglutamate form. The embryo assumes monoglutamates and immediately synthetises polyglutamates. In fact, these compounds are the only folate forms present in embryo and they increase progressively during development.
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