Abstract
Summary
Athymic nude mice appear to be an ideal animal model to demonstrate the local Shwartzman reaction; in these mice the reaction can be provoked by both endotoxin and double-stranded RNA.
This investigation was supported by grants from the F. G. W. O. (Fonds voor Geneeskundig Wetenschap-pelijk Onderzoek, krediet nr. 3.0048.75) and the Geconcerteerde Onderzoeksacties (Conventie nr. 76/81-IV). The authors are indebted to Dr. M. J. Van Stapel, Dr. C. Peeters and Prof. Dr. V. Desmet for histopathological examination of the skin biopsy specimens.
Get full access to this article
View all access options for this article.