Abstract
Summary
An enzyme-linked immunosorbent assay (ELISA) was developed for the detection of thyroglobulin antibodies. The ELISA was compared with an indirect hemagglutination technique using thyroglobulin coupled to human group O erythrocytes with chromic chloride. The overall correlation between the two techniques was 0.82 (P < 0.001). ELISA proved to be suitable for large-scale screening, as all reagents are stable, with a long shelf life. However, because of its lower sensitivity, it will probably not as yet replace the chromic chloride IHA test.
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