Abstract
Summary
The entire CMP content of regenerating rat liver was measured by radioimmunoassay. The concentration of cyclic CMP in normal liver was 7.2 ± 0.87 pmol/g wet weight. Eight hours after hepatectomy, this level had increased to 58.9 ± 10.0 pmol/g wet weight, and at 12 hr had reached a peak of 104.2 ± 19.0 pmol/g wet weight. By 16 hr, the cyclic CMP concentration had fallen to prehepatectomy levels. A second, smaller increase in the level of cyclic CMP occurred at 24-28 hr after operation, and by 48 hr the cyclic CMP had returned to prehepatectomy levels.
Get full access to this article
View all access options for this article.