Cl - Diffusion Potential of Nutrient Membrane of Frog Gastric Mucosa

Abstract

Summary

Replacement of Cl^- with SO₄ ^2- gives a Cl^- diffusion potential of about 19 mV across the nutrient membrane per 10-fold change in Cl^- concentration, suggesting, on the basis of the Nernst equation, that the Cl^- conductance pathway contributes about one-third to the total conductance of this membrane in regular Cl^- solutions bathing the frog gastric mucosa. Isethionate ion gives a change in PD of about 17 mV per 10-fold change which is quite close to the value obtained with SO₄ ^2-.