Abstract
Summary
The Halle strain of SSPE virus was found to consist of a heterogeneous population with regard to temperature sensitivity. Ten of 16 purified virus populations isolated from this strain were temperature sensitive (ts). The Halle strain was able to initiate persistent infection (PI) of HEp-2 cells at restrictive temperature but not at permissive temperature. The proportion of virus with ts properties did not increase with the passage of the persistently infected cells. No ts virus was detected in a strain of Edmonston measles virus, and this strain did not initiate PI at any temperature.
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