Abstract
Summary
Monocytes isolated from patients with active rheumatoid arthritis had elevated hexose monophosphate shunt (HMP) levels. Metabolic activity of blood monocytes incubated with rheumatoid sera was assessed by measuring hexose monophosphate shunt (HMP) levels. Sera from patients with rheumatoid arthritis enhanced HMP shunt activity of normal monocytes. These findings suggest that blood monocytes may be activated by circulating components present in rheumatoid sera.
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