Abstract
Summary
Disodium cromoglycate (DSCG) is absorbed from the lungs of the 6-day-old rat in part by a carrier-type transport process and in part by diffusion. The carrier process is saturated at DSCG concentrations greater than 25 mM and is inhibited by certain other organic anions including phenol red, benzylpenicillin, and p-aminohippuric acid. Although the carrier-mediated absorption process is present in the lungs of rats as young as 1 day of age, the process does not appear to become quantitatively mature until an age of 6 days when the transport rate is two to three times greater than that seen at the age of 1-3 days.
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