Abstract
Summary
The replacement of choline ions by Na+ ions in the secretory solution of the frog gastric mucosa of Rana pipiens in Cl--free media increases the resistance, the PD, and the H+ secretory rate. The replacement of Na+ by choline ions produces generally the reverse changes of the three electrophysiological parameters. The experimental data involving the PD and H+ secretory rate can be explained in terms of a Na+ emf in a Na+ conductance pathway opposing the H+ emf in a H+ conductance pathway on the secretory (apical) membrane.
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