Ovarian Growth and Uptake of lodinated D-Leu 6,des Gly NH 2 10 -LHRH Ethylamide in HCG Treated Rats 1 2

Abstract

Summary

Competitive uptake of labeled and unlabeled D-Leu⁶-LHRH-EA was observed in both the pituitary and ovary. HCG induced ovarian growth was inhibited by treating intact and hypophysectomized rats simultaneously with D-Leu⁶-LHRH-EA therefore, suggesting that D-Leu⁶-LHRH-EA acts directly on the ovary to inhibit HCG induced ovarian growth.