Abstract
Summary
Treatment of young and old male and female SH rats with bromoergo-cryptine (21 days) significantly reduced blood prolactin concentrations. Blood pressure was slightly depressed in young male SH rats whereas in females blood pressure was unchanged. Hypertension was reduced (30%) to normotensive levels in old rats of both sexes. Corticosterone levels were slightly affected by treatment. A significant drop in aldosterone levels was noted in young male SH rats exclusively. The hypotensive action of bromocryptine (a dopamine agonist) is uncertain but may be related to changes in catecholamine levels or actions within the central nervous system.
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