Abstract
Summary
Both uphill and downhill transport of calcium per unit weight of mucosa is decreased in duodenum of diabetic rats at 4 days of diabetes and shows a further decrease at 11 days. Absorption per duodenal segment is decreased in diabetics compared to controls despite much greater mucosal growth in diabetics. Calcium transport is normal in ileum of diabetic rats at 4 days, and only downhill transport is depressed at 11 days. Since the decreased absorption is the consequence of depressed 1,25-dihydroxyvitamin D in the diabetic rat, the data suggest that the ileum is more resistant to vitamin D depletion than the duodenum.
Get full access to this article
View all access options for this article.