Abstract
Summary
The influence of papaverine-HCl, a smooth muscle relaxant, on in vitro renin release was investigated. We demonstrated a papaverine-induced inhibition of renin release from renal cortical cell suspensions. This inhibition was significant when compared with the release of renin into control medium, at papaverine concentrations of 0.13 and 0.26 mM/1. No effect of papaverine on our radioimmunoassay procedures was found.
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