Abstract
Summary
The induction of differentiation in two Friend and two Rauscher virus-transformed proerythroid cell lines was studied. The benzidine assay for hemoglobin was used to determine differentiation. The Rauscher virus-transformed lines, RV-133 and RV-187, were induced to differentiate in the presence of eight known inducers, including dimethyl-sulfoxide, butyric acid, and N-methylpyrrolidone. One Friend virus-transformed line, FV-BDF1 did not differentiate on exposure to any inducer. The second Friend virus-transformed line, FV-BALB, differentiated only on exposure to N-methylpyrrolidone.
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