Abstract
Summary
The dietary induction of liver G6PD was found to be markedly impaired in the acute hepatic injury of rat caused by thioacetamide intoxication. The level of cyclic AMP in the injured liver was increased and could not be reduced by glucose-containing diets. The results indicated that the suppressed dietary inducibility of G6PD in hepatic injury is accounted for at least by the dietary unresponsive increase in cyclic AMP level in the injured liver.
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