Abstract
Summary
C-st phage which governs production of type C botulinum toxin was mixed at 4° with cells of C. botulinum type C and D cultures and nontoxigenics derived from them. The phage adsorbed to all three cultures producing type C toxin, the one type D toxin producer, 2 of 4 nontoxigenics from type C parents and the three nontoxigenics originating from type D toxin producers. The phage adsorbed to some cultures without converting to toxigenicity. The two nontoxigenic which could be converted to toxigenicity differed in degrees of phage adsorption and conversion rates.
Research was supported by the College of Agricultural and Life Sciences, University of Wisconsin, Madison, by NIH Grant No. FD00712, and contributions from food companies.
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