Abstract
Summary
Both the laboratory adapted Auburn strain and a recently isolated wild-type strain of channel catfish herpesvirus (CCV) were found to be inhibited by phosphonoacetic acid (PAA) when replicated in catfish cell cultures. The inhibition of virus cytopathic effect by PAA exhibited a direct relationship between the multiplicity of infection and amount of drug required. However, in this poikilothermic system up to 20 times the amount of PAA required for inhibition of homeothermic herpesvirus systems was found necessary to inhibit CCV cytopathology.
Get full access to this article
View all access options for this article.