The Anoxic Effect on 2-Deoxy-D-[ 3 H]Glucose Uptake in the Isolated Cerebral Capillaries 1

Abstract

Summary

The uptake of ³H 2-DG into the isolated cerebral capillaries was investigated under aerobic and anaerobic conditions. The capillary exposure to pure nitrogen atmosphere decreased the ³H 2-DG uptake. This reduction in ³H 2-DG uptake was either prevented by addition of FFA-free BSA into the incubating media under nitrogen or it could be recovered by substituting the nitrogen by oxygen containing gas mixture.