Abstract
Summary
The effect of Poly I: Poly C on the production of colony stimulating factor activity (CSA) by mononuclear cells (MNC) has been studied. Poly I: Poly C enhanced CSA production from whole blood buffy coat feeders, unseparated bone marrow (containing MNC) and from MNC incubations. Poly I: Poly C had no effect on separated bone marrow (devoid of MNC) stimulated with placental conditioned medium.
These experiments suggest that the colony enhancing effect of Poly I: Poly C is on the production of CSA and not the colony forming unit in culture.
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