Abstract
Summary
This study was an attempt to identify antigenic similarity between two estrogen binding proteins in the mouse; the uterine estrogen receptor and α-fetoprotein. The adsorption of these proteins onto an affinity resin containing immobilized anti-body to α-fetoprotein was tested. Alpha-fetoprotein could be selectively bound to this resin. On the other hand, estrogen receptor was only partially bound to the resin and this appeared to represent a nonspecific adsorption to the resin when tested against several control resins. Therefore, no antigenic similarity between these two proteins was observed.
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